The A Gleam Handicap is an American Thoroughbred horse race held annually in mid July at Hollywood Park Racetrack in Inglewood, California. Open to fillies and mares, age three and older, it is contested on Cushion Track synthetic dirt overr a distance of seven furlongs.

Inaugurated in 1941 as the Sequoia Handicap until 1979 when it was changed to the A Gleam Handicap in honor of Calumet Farm's filly, A Gleam, whose five stakes wins in 1952 is the co-record for most stakes race wins in a single meet at Hollywood Park. A Gleam was voted Hollywood Park's 1952 "Horse of the Meet."

The race was run at seven furlongs from inception until 1973 when it was modified to six furlongs. In 1983 it reverted to its original distance and has remained there since.

There was no race run in 1942-1943, and from 1947 through 1958.

In 2009, Evita Argentina became the first 3-year-old to win the A Gleam Handicap since -L Ranch Co.'s Honeymoon did it in 1946.